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Noribogaine also elevates serotonin concentrations from the brain, a attainable clarification for its antidepressive read more outcomes. The sustained presence of noribogaine in the CNS coupled with its here agonist action at opioid receptors may deliver the self-tapering influence in opiate-dependent individuals next abrupt discontinuation of opiates. Additionally, ibogaine can change the expression of several proteins, material P, and brain-derived neurotrophic issue. Noribogaine is likely to be much less neurotoxic than ibogaine.Litjens 2016
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